VAC14 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2735160

Produktdetails

Target: VAC14 (Vac14 Homolog (VAC14))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses VAC14 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human VAC14 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: VAC14 (Vac14 Homolog (VAC14))

Andere Bezeichnung: Vac14 (VAC14 Produkte)

Synonyme: ArPIKfyve Protein, TAX1BP2 Protein, TRX Protein, AA959718 Protein, BC032215 Protein, D8Wsu151e Protein, Tax1bp2 Protein, Trx Protein, ingls Protein, Vac14 homolog L homeolog Protein, Vac14, PIKFYVE complex component Protein, Vac14 homolog (S. cerevisiae) Protein, vac14.L Protein, VAC14 Protein, Vac14 Protein

Hintergrund: The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]).[supplied by OMIM, Feb 2010]

Molekulargewicht: 87.8 kDa

NCBI Accession: NP_060522

Pathways: Inositol Metabolic Process