Ccl21c Protein
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- Target
- Ccl21c (CCL21C) (Chemokine (C-C Motif) Ligand 21C (Leucine) (CCL21C))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Spezies
- Maus
- Quelle
- Escherichia coli (E. coli)
- Applikation
- Functional Studies (Func)
- Sequenz
- SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG
- Produktmerkmale
- Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine T-lymphocytes is in a concentration range of 10-100 ng/mL.
- Reinheit
- >97 % as determined by SDS-PAGE and HPLC.
- Sterilität
- 0.2 μm filtered
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
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- Target
- Ccl21c (CCL21C) (Chemokine (C-C Motif) Ligand 21C (Leucine) (CCL21C))
- Andere Bezeichnung
- Ccl21c
- Hintergrund
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Relevance: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs.
Synonyms: 6Ckine, Small-inducible cytokine A21c, Thymus-derived chemotactic agent 4, TCA4, - Molekulargewicht
- 12.1 kDa
- UniProt
- P86793
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