Indian Hedgehog Protein (IHH)

Produktnummer ABIN2830462

Dieses Recombinant Indian Hedgehog-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Indian Hedgehog Protein (IHH) (ABIN2830462)

Target: Indian Hedgehog (IHH)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Functional Studies (Func)

Reinheit: >96 % as determined by SDS-PAGE and HPLC.

Produktdetails

Sequenz: IIGPGRVVGS RRRPPRKLVP LAYKQFSPNV PEKTLGASGR YEGKIARSSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDRLNSLAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRNKYGLL ARLAVEAGFD WVYYESKAHV HCSVKSEHSA AAKTGG

Produktmerkmale: Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 3.0-10 μg/mL.

Sterilität: 0.2 μm filtered

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 20 mM PB, pH 7.4, 150 mM NaCl

Lagerung: -20 °C

Antigendetails

Target: Indian Hedgehog (IHH)

Andere Bezeichnung: IHH

Hintergrund: Relevance: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}.
Synonyms: IHH,

Molekulargewicht: 19.8 kDa

UniProt: Q14623

Pathways: Hedgehog Signalweg