Indian Hedgehog Protein (IHH)
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- Target Alle Indian Hedgehog (IHH) Proteine anzeigen
- Indian Hedgehog (IHH)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Applikation
- Functional Studies (Func)
- Sequenz
- IIGPGRVVGS RRRPPRKLVP LAYKQFSPNV PEKTLGASGR YEGKIARSSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDRLNSLAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRNKYGLL ARLAVEAGFD WVYYESKAHV HCSVKSEHSA AAKTGG
- Produktmerkmale
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 3.0-10 μg/mL.
- Reinheit
- >96 % as determined by SDS-PAGE and HPLC.
- Sterilität
- 0.2 μm filtered
- Top Product
- Discover our top product IHH Protein
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Indian Hedgehog (IHH) (AA 29-202) protein (His tag)
IHH Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Indian Hedgehog (IHH) (AA 28-202) protein (His tag)IHH Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Indian Hedgehog (IHH) (AA 203-411) protein (His tag)IHH Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 20 mM PB, pH 7.4, 150 mM NaCl
- Lagerung
- -20 °C
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- Target
- Indian Hedgehog (IHH)
- Andere Bezeichnung
- IHH (IHH Produkte)
- Hintergrund
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Relevance: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}.
Synonyms: IHH, - Molekulargewicht
- 19.8 kDa
- UniProt
- Q14623
- Pathways
- Hedgehog Signalweg
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