DR3/LARD Protein (AA 20-203) (Fc Tag)

Produktnummer ABIN2870800

Produktdetails

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-203

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses DR3/LARD Protein ist gelabelt mit Fc Tag.

Sequenz: AA 20-203

Produktmerkmale: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 46.3 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE).

Reinheit: >90 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Tris with Glycine, Arginine and NaCl,  pH 7.5

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Antigendetails

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Andere Bezeichnung: DR3 / TNFRSF25 (TNFRSF25 Produkte)

Synonyme: APO-3 Protein, DDR3 Protein, DR3 Protein, LARD Protein, TNFRSF12 Protein, TR3 Protein, TRAMP Protein, WSL-1 Protein, WSL-LR Protein, Tnfrsf12 Protein, Wsl Protein, TNFRSF25 Protein, TNF receptor superfamily member 25 Protein, tumor necrosis factor receptor superfamily, member 25 Protein, TNFRSF25 Protein, Tnfrsf25 Protein

Hintergrund: Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.

Molekulargewicht: 46.3 kDa

UniProt: G7NTB5

Pathways: Apoptose