WNT10A Protein, wnt10a/12 Protein, wnt10a Protein, OODD Protein, SSPS Protein, STHAG4 Protein, WNT-10A Protein, Wnt family member 10A Protein, protein Wnt-10a Protein, Wnt10a protein Protein, hypothetical protein Protein, WNT10A protein Protein, Wnt family member 10A L homeolog Protein, wingless-type MMTV integration site family, member 10A Protein, wingless-type MMTV integration site family, member 10a Protein, WNT10A Protein, LOC778792 Protein, CpipJ_CPIJ005839 Protein, Wnt10a Protein, wnt10a Protein, wnt10a.L Protein
Hintergrund
Synonyms: FLJ14301 Gene Description: wingless-type MMTV integration site family, member 10A Gene Name: WNT10A Gene Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. GenBank: AK315081.1, BAG37548.1