Biliverdin Reductase Protein (full length)

Produktnummer ABIN5021775

Produktdetails

Target: Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))

Protein-Typ: Native

Proteineigenschaft: full length

Spezies: Ratte

Quelle: Ratte

Applikation: SDS-PAGE (SDS), Western Blotting (WB)

Sequenz: MDAEPKRKFG VVVVGVGRAG SVRLRDLKDP RSAAFLNLIG FVSRRELGSL DEVRQISLED ALRSQEIDVA YICSESSSHE DYIRQFLQAG KHVLVEYPMT LSFAAAQELW ELAAQKGRVL HEEHVELLME EFEFLRREVL GKELLKGSLR FTASPLEEER FGFPAFSGIS RLTWLVSLFG ELSLISATLE ERKEDQYMKM TVQLETQNKG LLSWIEEKGP GLKRNRYVNF QFTSGSLEEV PSVGVNKNIF LKDQDIFVQK LLDQVSAEDL AAEKKRIMHC LGLASDIQKL CHQKK

Spezifität: ~36 kDa

Aufreinigung: Ion-exchange Purified

Reinheit: >90% pure using SDSPAGE analysis.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

This product has been certified >90% pure using SDSPAGE analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: 10 mM Tris pH 7.5, 0.1 mM EDTA, 0.2 mM DTT, 20 % glycerol

Lagerung: -80 °C

Antigendetails

Target: Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))

Andere Bezeichnung: BVR (BLVRA Produkte)

Synonyme: blvra Protein, MGC69310 Protein, BLVRA Protein, zgc:153046 Protein, BVR Protein, Dmel\\CG9471 Protein, BLVR Protein, BVRA Protein, 0610006A11Rik Protein, 2500001N03Rik Protein, Blvr Protein, biliverdin reductase A Protein, biliverdin reductase A L homeolog Protein, CG9471 gene product from transcript CG9471-RA Protein, BLVRA Protein, blvra Protein, blvra.L Protein, CG9471 Protein, Blvra Protein

Hintergrund: Biliverdin Reductase (BVR) is a cytoplasmic enzyme that catalyzes the conversion of biliverdin to bilirubin by converting a double bond between the second and third pyrrole ring into a single bond (1). It is ubiqutiously expressed in all tissues- it occurs in cells and brain regiuons that already display HO-1 and HO-2, but also in regions and cell types with potential to induce stress proteins. It is unique among all enzymes in having two pH optima, using a different cofactor at each pH range, NADH at pH 7.0 and NADPH at pH 8.7 (2). It is not inactivated by heat shock, and have shown to abate inflammation, oxidative stress and apoptosis (3).

Gen-ID: 116599

NCBI Accession: NP_446302

UniProt: P46844