INHBB Protein
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- Target Alle INHBB Proteine anzeigen
- INHBB (Inhibin, beta B (INHBB))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Hi-5 Cells
- Applikation
- Protein Interaction (PI), Standard (STD), Antibody Production (AbP), Functional Studies (Func)
- Spezifität
- Optimal preservation of protein structure, post-translational modifications and functions.
- Produktmerkmale
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- Recombinant human Inhibin beta B chain (INHBB) protein expressed in Hi-5 insect cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Reinheit
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin-Niveau
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- ED50 was determined by its ability to inhibit the proliferation of murine MPC-11 cells is less than or equal to 2.0 ng/ml, corresponding to a specific activity of > 5 x 10^5 units/mg.
- Top Product
- Discover our top product INHBB Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handhabung
- Resuspend the protein in the desired concentration in proper buffer
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- INHBB (Inhibin, beta B (INHBB))
- Andere Bezeichnung
- Inhibin beta B chain (INHBB) (INHBB Produkte)
- Synonyme
- actbb Protein, actbetaB Protein, inhibin Protein, inhibin, beta B Protein, inhibin beta B L homeolog Protein, inhibin beta B subunit Protein, inhibin beta B Protein, inhibin beta-B Protein, inhibin beta B chain Protein, inhbb Protein, inhbb.L Protein, INHBB Protein, Inhbb Protein, LOC100719829 Protein
- Hintergrund
- Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. [UniProtKB/Swiss-Prot Function]
- Molekulargewicht
- 25.6 kDa
- NCBI Accession
- NP_002184
- Pathways
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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