PSME3 Protein (PSME3) (partial) (His tag)
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- Target Alle PSME3 Proteine anzeigen
- PSME3
- Protein-Typ
- Recombinant
- Proteineigenschaft
- partial
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses PSME3 Protein ist gelabelt mit His tag.
- Applikation
- Western Blotting (WB)
- Sequenz
- Met 1 - Tyr 254
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Top Product
- Discover our top product PSME3 Protein
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- Applikationshinweise
- This recombinant protein can be used for WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 200 mM NaCl, pH 8.0
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Target
- PSME3
- Andere Bezeichnung
- PSME3 (PSME3 Produkte)
- Synonyme
- AA410043 Protein, AU020960 Protein, Ki Protein, PA28gamma Protein, REGgamma Protein, pa28g Protein, Ab2-371 Protein, PA28-gamma Protein, PA28G Protein, REG-GAMMA Protein, psme3b Protein, proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) Protein, proteasome activator subunit 3 Protein, proteasome activator subunit 3 S homeolog Protein, Psme3 Protein, PSME3 Protein, psme3.S Protein
- Hintergrund
- Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation.
- Molekulargewicht
- 30.3 kDa
- Gen-ID
- 10197
- NCBI Accession
- NP_00578
- UniProt
- P61289
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
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