IL-37 Protein (partial) (His tag)
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- Target Alle IL-37 (IL37) Proteine anzeigen
- IL-37 (IL37) (Interleukin 37 (IL37))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- partial
- Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses IL-37 Protein ist gelabelt mit His tag.
- Applikation
- Western Blotting (WB)
- Sequenz
- Val 46 - Asp 218
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Top Product
- Discover our top product IL37 Protein
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- Applikationshinweise
- This recombinant protein can be used for WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Target
- IL-37 (IL37) (Interleukin 37 (IL37))
- Andere Bezeichnung
- IL-37 (IL37 Produkte)
- Synonyme
- FIL1 Protein, FIL1(ZETA) Protein, FIL1Z Protein, IL-1F7 Protein, IL-1H Protein, IL-1H4 Protein, IL-1RP1 Protein, IL-37 Protein, IL1F7 Protein, IL1H4 Protein, IL1RP1 Protein, interleukin 37 Protein, IL37 Protein
- Hintergrund
- Interleukin-1 family member 7 (IL1F7b) ,a member of the IL-1 family, is aslo known as interleukin-37, interleukin-1 homolog 4 (IL-1H4), interleukin-1 zeta (IL-1 zeta) and interleukin-1-related protein, which can interact with SMAD3 and bind to IL18R1, but not to IL1R1, with lower affinity than IL18. IL1F7b is a suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Therefore,IL1F7b can suppress, or reduce, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spare anti-inflammatory cytokines. Furthermore,IL1F7b can also inhibit dendritic cell activation.
- Molekulargewicht
- 20.3 kDa
- Gen-ID
- 27178
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