Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Lagerung
-80 °C,4 °C,-20 °C
Informationen zur Lagerung
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target
CREB1
(cAMP Responsive Element Binding Protein 1 (CREB1))
creb Protein, CREB1 Protein, Creb1 Protein, CREB Protein, 2310001E10Rik Protein, 3526402H21Rik Protein, AV083133 Protein, Creb Protein, Creb-1 Protein, creb1 Protein, zgc:55598 Protein, cAMP responsive element binding protein 1 Protein, cAMP responsive element binding protein Protein, cAMP responsive element binding protein 1 S homeolog Protein, cAMP responsive element binding protein 1a Protein, CREB1 Protein, creb1 Protein, CREB Protein, Creb1 Protein, creb1.S Protein, creb1a Protein
Hintergrund
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response elent (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.