DNTTIP1
Spezies: Human
Wirt: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ELISA, SDS, WB
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Lagerung
-80 °C,4 °C,-20 °C
Informationen zur Lagerung
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target
DNTTIP1
(Deoxynucleotidyltransferase, Terminal, Interacting Protein 1 (DNTTIP1))
MGC79023 Protein, DNTTIP1 Protein, TDIF1 Protein, DKFZp469H0914 Protein, C20orf167 Protein, Tdif1 Protein, dJ447F3.4 Protein, 6430706C13Rik Protein, deoxynucleotidyltransferase terminal interacting protein 1 Protein, deoxynucleotidyltransferase, terminal, interacting protein 1 L homeolog Protein, deoxynucleotidyltransferase, terminal, interacting protein 1 Protein, DNTTIP1 Protein, dnttip1.L Protein, dnttip1 Protein, Dnttip1 Protein
Hintergrund
Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) . Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes, may recruit HDAC1 complexes to nucleosomes or naked DNA.