Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Lagerung
-80 °C,4 °C,-20 °C
Informationen zur Lagerung
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target
REG3g
(Regenerating Islet Derived Protein 3 gamma (REG3g))
LPPM429 Protein, PAP IB Protein, PAP-1B Protein, PAP1B Protein, PAPIB Protein, REG III Protein, REG-III Protein, UNQ429 Protein, AI449515 Protein, PAPIII Protein, Pap3 Protein, REG3A Protein, regenerating family member 3 gamma Protein, regenerating islet-derived 3 gamma Protein, REG3G Protein, Reg3g Protein
Hintergrund
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury .