SAMHD1
Spezies: Human
Wirt: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, ELISA, WB
SAMHD1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Lagerung
-80 °C,4 °C,-20 °C
Informationen zur Lagerung
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
CHBL2 Protein, DCIP Protein, HDDC1 Protein, MOP-5 Protein, SBBI88 Protein, si:dkeyp-44b8.8 Protein, E330031J07Rik Protein, Mg11 Protein, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Protein, SAM domain and HD domain 1 Protein, SAM domain and HD domain, 1 Protein, SAMHD1 Protein, samhd1 Protein, Samhd1 Protein
Hintergrund
Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling .