Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Lagerung
-80 °C,4 °C,-20 °C
Informationen zur Lagerung
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target
VAMP7
(Vesicle-Associated Membrane Protein 7 (VAMP7))
zgc:56506 Protein, sybl1 Protein, SYBL1 Protein, TI-VAMP Protein, TIVAMP Protein, VAMP-7 Protein, Sybl1 Protein, synaptobrevin-like 1 Protein, vesicle associated membrane protein 7 L homeolog Protein, vesicle associated membrane protein 7 Protein, vesicle-associated membrane protein 7 Protein, sybl1 Protein, vamp7.L Protein, VAMP7 Protein, Vamp7 Protein
Hintergrund
Involved in the targeting and/or fusion of transport vesicles to their target mbrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.