POU2AF1
Spezies: Human
Wirt: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, ELISA, WB
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Lagerung
-80 °C,4 °C,-20 °C
Informationen zur Lagerung
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target
POU2AF1
(POU Class 2 Associating Factor 1 (POU2AF1))
BOB1 Protein, OBF-1 Protein, OBF1 Protein, OCAB Protein, BOB-1 Protein, BOB.1 Protein, Bob-1 Protein, Bob1 Protein, OBF.1 Protein, OCA-B Protein, POU class 2 associating factor 1 Protein, POU domain, class 2, associating factor 1 Protein, POU2AF1 Protein, Pou2af1 Protein
Hintergrund
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.