CEP63
Spezies: Human
Wirt: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, ELISA, WB
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Lagerung
-80 °C,4 °C,-20 °C
Informationen zur Lagerung
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
4921501M07 Protein, AL450317.13gm1 Protein, AW107703 Protein, CD20R Protein, D9Mgc41 Protein, D9Mgc48e Protein, ET2 Protein, zgc:63548 Protein, Cep63-A Protein, Cep63-B Protein, Xcep63 Protein, centrosomal protein 63 Protein, centrosomal protein 63kDa Protein, centrosomal protein 63kDa L homeolog Protein, CEP63 Protein, SYO3AOP1_1060 Protein, Cep63 Protein, cep63 Protein, cep63.L Protein
Hintergrund
Required for normal spindle assbly. Plays a key role in mother-centriole-dependent centriole duplication, through centrosomal recruitment of CEP152. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is roved from centrosomes, this leads to the inactivation of spindle assbly and delay in mitotic progression.