KLRG1 Protein (AA 60-195, Extracellular) (His-SUMO Tag)

Produktnummer ABIN5711642

Produktdetails

Target: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Protein-Typ: Recombinant

Proteineigenschaft: Extracellular, AA 60-195

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses KLRG1 Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: LCQGSNYSTC ASCPSCPDRW MKYGNHCYYF SVEEKDWNSS LEFCLARDSH LLVITDNQEM SLLQVFLSEA FCWIGLRNNS GWRWEDGSPL NFSRISSNSF VQTCGAINKN GLQASSCEVP LHWVCKKCPF ADQALF

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Andere Bezeichnung: KLRG1 (KLRG1 Produkte)

Synonyme: KLRG1 Protein, 2F1-Ag Protein, MAFA Protein, MAFA-L Protein, 2F1 Protein, CLEC15A Protein, MAFA-2F1 Protein, MAFA-LIKE Protein, killer cell lectin like receptor G1 Protein, killer cell lectin-like receptor subfamily G, member 1 Protein, KLRG1 Protein, Klrg1 Protein

Hintergrund: Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.

Molekulargewicht: 31.5 kDa

UniProt: Q96E93