ARNT Protein (AA 1-474, partial) (His tag)

Produktnummer ABIN5713256

Produktdetails

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Protein-Typ: Recombinant

Proteineigenschaft: partial, AA 1-474

Spezies: Human

Quelle: Hefe

Aufreinigungstag / Konjugat: Dieses ARNT Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS CETGRVVYVS DSVTPVLNQP QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK TGTVKKEGQQ SSMRMCMGSR RSFICRMRCG SSSVDPVSVN RLSFVRNRCR NGLGSVKDGE PHFVVVHCTG YIKAWPPAGV SLPDDDPEAG QGSKFCLVAI GRLQVTSSPN CTDMSNVCQP TEFISRHNIE GIFTFVDHRC VATVGYQPQE LLGKNIVEFC HPEDQQLLRD SFQQVVKLKG QVLSVMFRFR SKNQEWLWMR TSSFTFQNPY SDEIEYIICT NTNVKNSSQE PRPT

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Andere Bezeichnung: ARNT (ARNT Produkte)

Synonyme: HIF-1-beta Protein, HIF-1beta Protein, HIF1-beta Protein, HIF1B Protein, HIF1BETA Protein, TANGO Protein, bHLHe2 Protein, D3Ertd557e Protein, Drnt Protein, ESTM42 Protein, Hif1b Protein, W08714 Protein, mKIAA4051 Protein, Arnt1 Protein, ARNT Protein, zgc:136664 Protein, arnt1 Protein, hif1b Protein, tango Protein, xArnt Protein, hif1beta Protein, hif-1beta Protein, arnt.2 Protein, MGC68805 Protein, aryl hydrocarbon receptor nuclear translocator Protein, aryl hydrocarbon receptor nuclear translocator S homeolog Protein, ARNT Protein, Arnt Protein, arnt Protein, arnt.S Protein

Hintergrund: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

Molekulargewicht: 54.83 kDa

UniProt: P27540

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt