CD8B Protein (AA 564-1049) (His tag)

Produktnummer ABIN5778807

Produktdetails

Target: CD8B (CD8b Molecule (CD8B))

Protein-Typ: Recombinant

Proteineigenschaft: AA 564-1049

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses CD8B Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADPLQQTPAY IKVQTNKMVM LSCEAKISLS NMRIYWLRQR QAPSSDSHHE FLALWDSAKG TIHGEEVEQE KIAVFRDASR FILNLTSVKP EDSGIYFCMI VGSPELTFGK GTQLSVVDFL PTTAQPTKKS TLKKRVCRLP RPETQKGPLC SPHHHHHH

Reinheit: > 85 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CD8B (CD8b Molecule (CD8B))

Andere Bezeichnung: CD8B (CD8B Produkte)

Synonyme: Cd8b Protein, Ly-3 Protein, Ly-C Protein, Lyt-3 Protein, CD8B1 Protein, LEU2 Protein, LY3 Protein, LYT3 Protein, P37 Protein, Cd8b1 Protein, CD8b molecule Protein, CD8 antigen, beta chain 1 Protein, Cd8b Protein, CD8B Protein, Cd8b1 Protein

Hintergrund: CD8B, also known as T-cell surface glycoprotein CD8 beta chain isoform 5, is a cell surface transmembrane glycoprotein. This protein serves as a co-receptor for the T cell receptor (TCR). It found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-alpha and CD8-beta chain. Both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail. Recombinant human CD8B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 17.8kDa (158aa) 18-28kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_004922

UniProt: P10966

Pathways: T-Zell Rezeptor Signalweg