HLA-DOA Protein (AA 26-217) (His tag)
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- Target Alle HLA-DOA Proteine anzeigen
- HLA-DOA (HLA Class II DO alpha (HLA-DOA))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 26-217
- Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses HLA-DOA Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MGSSHHHHHH SSGLVPRGSH MGSTKADHMG SYGPAFYQSY GASGQFTHEF DEEQLFSVDL KKSEAVWRLP EFGDFARFDP QGGLAGIAAI KAHLDILVER SNRSRAINVP PRVTVLPKSR VELGQPNILI CIVDNIFPPV INITWLRNGQ TVTEGVAQTS FYSQPDHLFR KFHYLPFVPS AEDVYDCQVE HWGLDAPLLR HWELQVPIPP PDAME
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HLA-DOA Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Denatured
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- HLA-DOA (HLA Class II DO alpha (HLA-DOA))
- Andere Bezeichnung
- HLA-DOA (HLA-DOA Produkte)
- Synonyme
- HLA-DNA Protein, HLA-DZA Protein, HLADZ Protein, major histocompatibility complex, class II, DO alpha Protein, HLA-DOA Protein
- Hintergrund
- HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. Recombinant human HLA-DAO protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 24.1 kDa (215aa)
- NCBI Accession
- NP_002110
- UniProt
- P06340
- Pathways
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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