FUT3 Protein (AA 35-361) (His tag)

Produktnummer ABIN5853233

Produktdetails

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 35-361

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FUT3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSRVSRDDA TGSPRAPSGS SRQDTTPTRP TLLILLWTWP FHIPVALSRC SEMVPGTADC HITADRKVYP QADTVIVHHW DIMSNPKSRL PPSPRPQGQR WIWFNLEPPP NCQHLEALDR YFNLTMSYRS DSDIFTPYGW LEPWSGQPAH PPLNLSAKTE LVAWAVSNWK PDSARVRYYQ SLQAHLKVDV YGRSHKPLPK GTMMETLSRY KFYLAFENSL HPDYITEKLW RNALEAWAVP VVLGPSRSNY ERFLPPDAFI HVDDFQSPKD LARYLQELDK DHARYLSYFR WRETLRPRSF SWALDFCKAC WKLQQESRYQ TVRSIAAWFT

Reinheit: > 80 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Denatured

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Andere Bezeichnung: FuT3 (FUT3 Produkte)

Synonyme: CD174 Protein, FT3B Protein, FucT-III Protein, LE Protein, Les Protein, fut356 Protein, FUT3 Protein, ATFUT3 Protein, F1M20.10 Protein, F1M20_10 Protein, fucosyltransferase 3 Protein, fucosyltransferase 3 (Lewis blood group) Protein, fucosyltransferase 3 (Lewis blood group) L homeolog Protein, fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) Protein, fucosyltransferase 3 Protein, galactoside 3(4)-L-fucosyltransferase Protein, FUT3 Protein, fut3.L Protein, fut3 Protein, LOC697452 Protein, LOC697582 Protein

Hintergrund: Fucosyltransferase 3, also known as FuT3, may catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. This protein may be involved in blood group Lewis determination, Lewis-positive (Le+) individuals have an active enzyme while Lewis-negative (Le-) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links. Recombinant human FuT3 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 40.6 kDa (350aa)

NCBI Accession: NP_001091110

UniProt: P21217