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TIMM8A/DDP Protein (AA 1-97) (His tag)
TIMM8A
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
Produktnummer ABIN5853449
Produktdetails
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Target
Alle TIMM8A/DDP (TIMM8A) Proteine anzeigen
TIMM8A/DDP (TIMM8A)
(Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
Protein-Typ
Recombinant
Proteineigenschaft
AA 1-97
Spezies
Alle Spezies für TIMM8A/DDP Proteine
Human
Quelle
Alle Expressionssysteme für TIMM8A/DDP Proteine
Escherichia coli (E. coli)
Aufreinigungstag / Konjugat
Dieses TIMM8A/DDP Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Sequenz
MGSSHHHHHH SSGLVPRGSH MGSMDSSSSS SAAGLGAVDP QLQHFIEVET QKQRFQQLVH QMTELCWEKC MDKPGPKLDS RAEACFVNCV ERFIDTSQFI LNRLEQTQKS KPVFSESLSD
Reinheit
> 90 % by SDS - PAGE
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Discover our top product TIMM8A Protein
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 30 % glycerol, 1 mM DTT
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Antigendetails
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Target
TIMM8A/DDP (TIMM8A)
(Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
Andere Bezeichnung
TIMM8A (TIMM8A Produkte )
Synonyme
TIMM8A Protein, ddp Protein, tim8a Protein, timm8a Protein, DDP Protein, DDP1 Protein, DFN1 Protein, MTS Protein, TIM8 Protein, im:6896085 Protein, zgc:100916 Protein, Ddp1 Protein, Timm8a Protein, DXHXS1274E Protein, Fci-12 Protein, Tim8a Protein, translocase of inner mitochondrial membrane 8 homolog A (yeast) Protein, translocase of inner mitochondrial membrane 8A Protein, translocase of inner mitochondrial membrane 8 homolog A1 (yeast) Protein, translocase of inner mitochondrial membrane 8A1 Protein, TIMM8A Protein, timm8a Protein, Timm8a1 Protein
Hintergrund
TIMM8A is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome, an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Recombinant human TIMM8A proten, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Molekulargewicht
13.4kDa (120aa) confirmed by MALDI-TOF
NCBI Accession
NP_004076
UniProt
O60220
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