TARBP2 Protein (AA 1-345)

Produktnummer ABIN5853732

Produktdetails

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-345

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Sequenz: MLAANPGKTP ISLLQEYGTR IGKTPVYDLL KAEGQAHQPN FTFRVTVGDT SCTGQGPSKK AAKHKAAEVA LKHLKGGSML EPALEDSSSF SPLDSSLPED IPVFTAAAAA TPVPSVVLTR SPPMELQPPV SPQQSECNPV GALQELVVQK GWRLPEYTVT QESGPAHRKE FTMTCRVERF IEIGSGTSKK LAKRNAAAKM LLRVHTVPLD ARDGNEVEPD DDHFSIGVGS RLDGLRNRGP GCTWDSLRNS VGEKILSLRS CSLGSLGALG PACCRVLSEL SEEQAFHVSY LDIEELSLSG LCQCLVELST QPATVCHGSA TTREAARGEA ARRALQYLKI MAGSK

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Denatured

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol 0.4M urea

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Andere Bezeichnung: TARBP2 (TARBP2 Produkte)

Synonyme: trbp Protein, trbp1 Protein, trbp2 Protein, MGC97783 Protein, TARBP2 Protein, LOQS Protein, TRBP Protein, TRBP1 Protein, TRBP2 Protein, fj51e12 Protein, wu:fj51e12 Protein, zgc:63778 Protein, Prbp Protein, TAR (HIV-1) RNA binding protein 2 Protein, TARBP2, RISC loading complex RNA binding subunit Protein, TAR (HIV-1) RNA binding protein 2 L homeolog Protein, TAR (HIV) RNA binding protein 2 Protein, tarbp2 Protein, TARBP2 Protein, tarbp2.L Protein, Tarbp2 Protein

Hintergrund: TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. This protein contains 3 DRBM (double-stranded RNA-binding) domains. It may also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. TARBP2 binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. Recombinant human TARBP2 protein was expressed in E.coli.

Molekulargewicht: 36.9 kDa (345aa)

NCBI Accession: NP_004169

UniProt: Q15633

Pathways: Regulatorische RNA Pathways, Ribonucleoprotein Complex Subunit Organization