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PEBP1 Protein (AA 1-187) (His tag)
PEBP1
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % by SDS - PAGE
SDS
Produktnummer ABIN5854348
Produktdetails
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Target
Alle PEBP1 Proteine anzeigen
PEBP1
(Phosphatidylethanolamine Binding Protein 1 (PEBP1))
Protein-Typ
Recombinant
Proteineigenschaft
AA 1-187
Spezies
Alle Spezies für PEBP1 Proteine
Maus
Quelle
Alle Expressionssysteme für PEBP1 Proteine
Escherichia coli (E. coli)
Aufreinigungstag / Konjugat
Dieses PEBP1 Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Sequenz
MGSSHHHHHH SSGLVPRGSH MGSMAADISQ WAGPLCLQEV DEPPQHALRV DYAGVTVDEL GKVLTPTQVM NRPSSISWDG LDPGKLYTLV LTDPDAPSRK DPKFREWHHF LVVNMKGNDI SSGTVLSDYV GSGPPSGTGL HRYVWLVYEQ EQPLSCDEPI LSNKSGDNRG KFKVETFRKK YNLGAPVAGT CYQAEWDDYV PKLYEQLSGK
Reinheit
> 95 % by SDS - PAGE
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Discover our top product PEBP1 Protein
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Antigendetails
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Target
PEBP1
(Phosphatidylethanolamine Binding Protein 1 (PEBP1))
Andere Bezeichnung
Pebp1 (PEBP1 Produkte )
Synonyme
HCNP Protein, HCNPpp Protein, PBP Protein, PEBP Protein, PEBP-1 Protein, RKIP Protein, pbp Protein, hcnp Protein, pebp Protein, rkip Protein, Pbp Protein, Pbp1 Protein, Pbpr Protein, Rkip Protein, PEBP1 Protein, BcDNA:LP12095 Protein, CG18594 Protein, Dmel\\CG18594 Protein, T2 Protein, zgc:56033 Protein, zgc:76942 Protein, phosphatidylethanolamine binding protein 1 Protein, phosphatidylethanolamine binding protein 1 L homeolog Protein, phosphatidylethanolamine-binding protein Protein, phosphatidylethanolamine-binding protein,putative Protein, Phosphatidylethanolamine-binding protein 1 Protein, PEBP1 Protein, pebp1 Protein, Pebp1 Protein, pebp1.L Protein, RR_RS07785 Protein, PVX_235290 Protein, PVX_123630 Protein, PKH_143640 Protein, EAM_1207 Protein
Hintergrund
Pebp1 also known as Phosphatidylethanolamine-binding protein 1. The protein Binds with ATP, opioids and phosphatidylethanolamine. Pebp1 exerts inhibitory activity against several serine proteases including thrombin, neuropsin, and chymotrypsin, it also inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. Also, targeting Pebp1 levels can delay photoreceptor degeneration, assisting in extending the time-window for treating such rapidly progressing blindness disorder. Recombinant mouse Pebp1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Molekulargewicht
23.2kDa (210aa) confirmed by MALDI-TOF
NCBI Accession
NP_061346
UniProt
P70296
Pathways
Feeding Behaviour
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