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Cadherin 5 Protein (CDH5) (AA 29-599) (hIgG-His-tag)
CDH5
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
Produktnummer ABIN5854789
Produktdetails
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Target
Alle Cadherin 5 (CDH5) Proteine anzeigen
Cadherin 5 (CDH5)
Protein-Typ
Recombinant
Proteineigenschaft
AA 29-599
Spezies
Alle Spezies für Cadherin 5 Proteine
Human
Quelle
Alle Expressionssysteme für Cadherin 5 Proteine
Baculovirus infected Insect Cells
Aufreinigungstag / Konjugat
Dieses Cadherin 5 Protein ist gelabelt mit hIgG-His-tag.
Applikation
SDS-PAGE (SDS)
Sequenz
NPAQRDTHSL LPTHRRQKRD WIWNQMHIDE EKNTSLPHHV GKIKSSVSRK NAKYLLKGEY VGKVFRVDAE TGDVFAIERL DRENISEYHL TAVIVDKDTG ENLETPSSFT IKVHDVNDNW PVFTHRLFNA SVPESSAVGT SVISVTAVDA DDPTVGDHAS VMYQILKGKE YFAIDNSGRI ITITKSLDRE KQARYEIVVE ARDAQGLRGD SGTATVLVTL QDINDNFPFF TQTKYTFVVP EDTRVGTSVG SLFVEDPDEP QNRMTKYSIL RGDYQDAFTI ETNPAHNEGI IKPMKPLDYE YIQQYSFIVE ATDPTIDLRY MSPPAGNRAQ VIINITDVDE PPIFQQPFYH FQLKENQKKP LIGTVLAMDP DAARHSIGYS IRRTSDKGQF FRVTKKGDIY NEKELDREVY PWYNLTVEAK ELDSTGTPTG KESIVQVHIE VLDENDNAPE FAKPYQPKVC ENAVHGQLVL QISAIDKDIT PRNVKFKFIL NTENNFTLTD NHDNTANITV KYGQFDREHT KVHFLPVVIS DNGMPSRTGT STLTVAVCKC NEQGEFTFCE DMAAQVGVSI QLEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SRDELTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGKHHHHHH
Reinheit
> 90 % by SDS - PAGE
Endotoxin-Niveau
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Antigendetails
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Target
Cadherin 5 (CDH5)
Andere Bezeichnung
CDH5 (CDH5 Produkte )
Synonyme
7B4 Protein, AA408225 Protein, Cd144 Protein, VE-Cad Protein, VECD Protein, VEcad Protein, Vec Protein, wu:fc88a07 Protein, CD144 Protein, cadherin-5 Protein, cadherin 5 Protein, CDH5 Protein, Cdh5 Protein, cdh5 Protein
Hintergrund
CDH5, as known as cadherin-5, is a member of the atypical/type 2 subgroup of Cadherin homophilic adhesion proteins. This protein plays a role in the formation, maturation and remodeling of the vascular wall. It is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. Also, this protein regulates or is regulated by VEGF R2, type 1 and type 2 TGF-beta receptors, and other endothelial junction proteins such as JAM-C, Claudin-5, and N-Cadherin. Recombinant human CDH5, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Molekulargewicht
91.5kDa (810aa) 70-100kDa (SDS-PAGE under reducing conditions.)
NCBI Accession
NP_001786
UniProt
P33151
Pathways
Cell-Cell Junction Organization , Signaling Events mediated by VEGFR1 and VEGFR2
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