YOD1 Protein (His tag)
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- Target Alle YOD1 Proteine anzeigen
- YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses YOD1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Aufreinigung
- purified by chromatography
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product YOD1 Protein
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- Kommentare
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Synonyms: Ubiquitin thioesterase OTU1, DUBA8, OTUD2, PRO0907, RP11-164O23.1
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 30% glycerol, 1 MM DTT
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))
- Andere Bezeichnung
- YOD1 (YOD1 Produkte)
- Synonyme
- DUBA8 Protein, OTUD2 Protein, PRO0907 Protein, hshin7 Protein, wu:fe01a10 Protein, zgc:112182 Protein, 9930028C20Rik Protein, Hshin7 Protein, YOD1 deubiquitinase Protein, YOD1 deubiquitinase L homeolog Protein, YOD1 Protein, Yod1 Protein, yod1.L Protein, yod1 Protein
- Hintergrund
- YOD1 is a highly conserved deubiquitinating enzyme of the ovarian tumor (otubain) family, whose function has yet to be assigned in mammalian cells. YOD1 is a constituent of a multiprotein complex with p97 as its nucleus, suggesting a functional link to a pathway responsible for the dislocation of misfolded proteins from the endoplasmic reticulum. Expression of a YOD1 variant deprived of its deubiquitinating activity imposes a halt on the dislocation reaction, as judged by the stabilization of various dislocation substrates. Recombinant human YOD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molekulargewicht
- 40.7 kDa (371aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_061036
- Pathways
- ER-Nucleus Signaling
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