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EEF2K Protein (AA 1-725) (His tag)
EEF2K
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 85 % by SDS - PAGE
SDS
Produktnummer ABIN6387490
Produktdetails
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Target
Alle EEF2K Proteine anzeigen
EEF2K
(Eukaryotic Elongation Factor-2 Kinase (EEF2K))
Protein-Typ
Recombinant
Proteineigenschaft
AA 1-725
Spezies
Alle Spezies für EEF2K Proteine
Human
Quelle
Alle Expressionssysteme für EEF2K Proteine
Escherichia coli (E. coli)
Aufreinigungstag / Konjugat
Dieses EEF2K Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Sequenz
MGSSHHHHHH SSGLVPRGSH MGSMADEDLI FRLEGVDGGQ SPRAGHDGDS DGDSDDEEGY FICPITDDPS SNQNVNSKVN KYYSNLTKSE RYSSSGSPAN SFHFKEAWKH AIQKAKHMPD PWAEFHLEDI ATERATRHRY NAVTGEWLDD EVLIKMASQP FGRGAMRECF RTKKLSNFLH AQQWKGASNY VAKRYIEPVD RDVYFEDVRL QMEAKLWGEE YNRHKPPKQV DIMQMCIIEL KDRPGKPLFH LEHYIEGKYI KYNSNSGFVR DDNIRLTPQA FSHFTFERSG HQLIVVDIQG VGDLYTDPQI HTETGTDFGD GNLGVRGMAL FFYSHACNRI CESMGLAPFD LSPRERDAVN QNTKLLQSAK TILRGTEEKC GSPRVRTLSG SRPPLLRPLS ENSGDENMSD VTFDSLPSSP SSATPHSQKL DHLHWPVFSD LDNMASRDHD HLDNHRESEN SGDSGYPSEK RGELDDPEPR EHGHSYSNRK YESDEDSLGS SGRVCVEKWN LLNSSRLHLP RASAVALEVQ RLNALDLEKK IGKSILGKVH LAMVRYHEGG RFCEKGEEWD QESAVFHLEH AANLGELEAI VGLGLMYSQL PHHILADVSL KETEENKTKG FDYLLKAAEA GDRQSMILVA RAFDSGQNLS PDRCQDWLEA LHWYNTALEM TDCDEGGEYD GMQDEPRYMM LAREAEMLFT GGYGLEKDPQ RSGDLYTQAA EAAMEAMKGR LANQYYQKAE EAWAQMEE
Reinheit
> 85 % by SDS - PAGE
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
Liquid. In Phosphate buffered saline ( pH 7.4), 10 % glycerol
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Antigendetails
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Target
EEF2K
(Eukaryotic Elongation Factor-2 Kinase (EEF2K))
Andere Bezeichnung
EEF2K (EEF2K Produkte )
Synonyme
HSU93850 Protein, eEF-2K Protein, C86191 Protein, SMEF2K Protein, eEF-2 kinase Protein, cb365 Protein, fa04b08 Protein, wu:fa04b08 Protein, zgc:100973 Protein, eukaryotic elongation factor 2 kinase Protein, eukaryotic elongation factor-2 kinase Protein, EEF2K Protein, Eef2k Protein, eef2k Protein, LOC101930123 Protein
Hintergrund
Eukaryotic elongation factor-2 kinase, also known as EEF2K, is threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. Recombinant human EEF2K protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Molekulargewicht
84.6 kDa (748aa)
NCBI Accession
NP_037434
UniProt
O00418
Pathways
AMPK Signaling
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