Galectin 2 Protein (AA 1-130) (His tag)
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- Target Alle Galectin 2 (LGALS2) Proteine anzeigen
- Galectin 2 (LGALS2) (Lectin, Galactoside-Binding, Soluble, 2 (LGALS2))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 1-130
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Galectin 2 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MGSSHHHHHH SSGLVPRGSH MGSMSEKFEV KDLNMKPGMS LKIKGKIHND VDRFLINLGQ GKETLNLHFN PRFDESTIVC NTSEGGRWGQ EQRENHMCFS PGSEVKITIT FQDKDFKVTL PDGHQLTFPN RLGHNQLHYL SMGGLQISSF KLE
- Reinheit
- > 95 % by SDS - PAGE
- Biological Activity Comment
- The ED50 for this effect is equal or higher than 20 ug/ml. Measured by its ability to agglutinate human red blood cells.
- Top Product
- Discover our top product LGALS2 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Bioactivity Validated
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.1M NaCl, 10 % glycerol,1 mM DTT
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Galectin 2 (LGALS2) (Lectin, Galactoside-Binding, Soluble, 2 (LGALS2))
- Andere Bezeichnung
- Lgals2 (LGALS2 Produkte)
- Synonyme
- LGALS3 Protein, galectin-2 Protein, HL14 Protein, 2200008F12Rik Protein, AI324147 Protein, LGALS2 Protein, hl14 Protein, Drgal1-L3 Protein, lgals1l3 Protein, zgc:66283 Protein, Drgal1-L2 Protein, lgals1l2 Protein, zgc:86752 Protein, galectin 2 Protein, lectin, galactose-binding, soluble 2 Protein, lectin, galactoside binding soluble 2 Protein, lectin, galactoside-binding, soluble, 2b Protein, lectin, galactoside-binding, soluble, 2a Protein, LGALS2 Protein, Lgals2 Protein, lgals2 Protein, lgals2b Protein, lgals2a Protein
- Hintergrund
- Galectin 2, also known as Lgals2, belongs to the galectins family. Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Lgals2 is a monomeric or homodimeric prototype galectin that is expressed in hepatoma, stomach epithelial cells and in colorectal and neural tumors. It induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-a (LTA) with possible implications in risk of myocardial infarction. Human and mouse Lgals2 share approximately 65 % amino acid sequence similarity. Recombinant Mouse Lgals2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molekulargewicht
- 17.3 kDa (153aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_079898
- UniProt
- Q9CQW5
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