PSMF1 Protein (AA 1-271) (His tag)

Produktnummer ABIN666623

Produktdetails

Target: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-271

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PSMF1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: PSMF1, 1-271aa , Human, His tag E.coli

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT,0.1mM PMSF

Lagerung: 4 °C

Antigendetails

Target: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Andere Bezeichnung: PSMF1 (PSMF1 Produkte)

Synonyme: PI31 Protein, AW048666 Protein, BC012260 Protein, zgc:92785 Protein, proteasome inhibitor subunit 1 Protein, proteasome (prosome, macropain) inhibitor subunit 1 Protein, PSMF1 Protein, Psmf1 Protein, psmf1 Protein

Hintergrund: PSMF1 is a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Recombinant human PSMF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Proteasome inhibitor subunit 1 isoform 1, PI31. NCBI no.: NP_006805

Molekulargewicht: 31.9 kDa (291aa), confirmed by MALDI-TOF

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA