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PIN1 Protein

PIN1 Spezies: Human Wirt: Escherichia coli (E. coli) 95 % by SDS - PAGE SDS
Produktnummer ABIN666676
  • Target Alle PIN1 Proteine anzeigen
    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
    Spezies
    • 10
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 9
    • 6
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    Pin 1(Peptidyl-prolyl cis/trans isomerase) Human, Recombinant, E.coli
    Reinheit
    95 % by SDS - PAGE
    Top Product
    Discover our top product PIN1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer(pH7.5) 0.1M NaCl, 5mM DTT, 20%Glycerol.
    Lagerung
    4 °C
  • Target
    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
    Abstract
    PIN1 Produkte
    Synonyme
    DOD Protein, UBL5 Protein, dod Protein, ubl5 Protein, pin1 Protein, pin1a Protein, 0610025L01Rik Protein, D9Bwg1161e Protein, pin1b Protein, zgc:73206 Protein, PPIase pin1 Protein, MdPin1 Protein, Pin1 Protein, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Protein, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog Protein, protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 Protein, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog Protein, peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Protein, peptidyl-prolyl cis-trans isomerase Pin1 Protein, PIN1 Protein, Pin1 Protein, pin1 Protein, pin1.S Protein, pin1.L Protein, ppiD Protein, PITG_11123 Protein, LOC103419188 Protein
    Hintergrund
    Human Pin 1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA ,PLK I, Wee, and Myt1 kinases), several transcription factors like beta-Catenin, c-Jun, and the tumor suppressor protein p53 , and some specific proteins like the RNA Pol II, the cytoskeleton protein tau, and the G1/S protein Cyclin D1. Synonyms: PIN1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, EC 5.2.1.8, Rotamase Pin1, PPIase Pin1, DOD, UBL5, PIN1, PPIase, EC 5.2.1.8, Rotamase Pin1, PPIase Pin1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1. NCBI no.: NP_006212
    Molekulargewicht
    18.2 kDa (163 aa), confirmed by MALDI-TOF.
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