Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Recombinant human cyclophilin B was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PPIB, Peptidylprolyl isomerase B, CYPB, SCYLP, CYP-S1: Cyclophilin-B, Cyclophilin B, 26- 216aa , AA553318, AI844835, Cphn 2, Cphn2, CyP 20b, AA408962, CYP S1, MGC14109, MGC2224, peptidyl prolyl cis trans isomerase B, Peptidyl prolyl cis trans isomerase B precursor, PPIase, Rotamase, S cyclophilin. NCBI no.: NP_000933