bmp-7 Protein, bmp7 Protein, op-1 Protein, BMP7 Protein, zgc:153025 Protein, OP-1 Protein, OP1 Protein, BMP-7 Protein, fb83f09 Protein, wu:fb83f09 Protein, bone morphogenetic protein 7 Protein, bone morphogenetic protein 7, gene 1 L homeolog Protein, bone morphogenetic protein 7b Protein, bone morphogenetic protein 7, gene 2 L homeolog Protein, bone morphogenetic protein 7a Protein, BMP7 Protein, bmp7.1.L Protein, LOC100136282 Protein, bmp7b Protein, Bmp7 Protein, LOC100008826 Protein, bmp7.2.L Protein, bmp7a Protein
Hintergrund
Bone morphogenic protein-7 (BMP-7/OP-1) is a member of the transforming growth factor-beta (TGF-beta) superfamily. Like other members of the BMPs family, it plays a role in calcium regulation and bone homeostasis. BMPs have been also shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. BMP7 also has the potential for treatment of chronic kidney disease. Recombinant human BMP-7 protein was expressed in E.coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer. Synonyms: Osteogenic protein1, OP-1, Bone morphogenetic protein 7 BMP 7, Eptotermin alfa, OP 1, OP1. NCBI no.: NP_001710