TTR Protein (AA 21-147)

Produktnummer ABIN666931

Recombinant TTR-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für TTR Protein (AA 21-147) (ABIN666931)

Target: TTR (Transthyretin (TTR))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 % by SDS - PAGE

Produktdetails

Proteineigenschaft: AA 21-147

Produktmerkmale: Prealbumin, 21-147aa, Human, E.coli

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol

Lagerung: 4 °C

Antigendetails

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: Prealbumin

Hintergrund: Prealbumin, also known Transthyretin, is a tetrameric human plasma protein that is synthesized mainly in the liver. This protein transports the thyroid hormone thyroxine (T4) and retinol (Vitamin A). It is the best indicator of protein-energy malnutrition because it has a circulating half life of 2 days and responds rapidly to changes in nutritional status. Also point-mutations of its gene are known to be associated with the amyloid diseases senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC). Recombinant human Prealbumin was expressed in E.coli and purified by using conventional chromatography. Synonyms: TTR, Transthyretin, TBPA, ATTR, PALB, Amyloid polyneuropathy, Amyloidosis I, Dysprealbuminemic euthyroidal hyperthyroxinemia, Dystransthyretinemic hyperthyroxinemia, HsT2651, Prealbumin amyloidosis type I, Senile systemic amyloidosis, TTR protein. NCBI no.: NP_000362

Molekulargewicht: 13.8 kDa (128aa), confirmed by MALDI-TOF.

Pathways: Hormone Transport