LAT2
Spezies: Human
Wirt: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
WB, SDS, ELISA
LAB Protein, NTAL Protein, WBSCR15 Protein, WBSCR5 Protein, WSCR5 Protein, LAT2 Protein, MGC139435 Protein, Ntal Protein, Wbscr5 Protein, AW125574 Protein, Wbscr15 Protein, linker for activation of T-cells family member 2 Protein, linker for activation of T cells family, member 2 Protein, LAT2 Protein, Lat2 Protein
Hintergrund
NTAL (non-T cell activation linker), as known as LAT2, is transmembrane adaptor protein (TRAP) associated with glycolipid-enriched membrane fractions (GEM or lipid rafts). This protein is primarily expressed in spleen and hematopoietic cells, such as B cells, mast cells, NK cells, and monocytes, but not resting T cells. Defects in NTAL may be a cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS). Recombinant human NTAL, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: LAT2, HSPC046, LAB, WBSCR15, WBSCR5, WSCR5, Non-T-cell activation linker LAB, Lat2, Linker for activation of B cells, Linker for activation of T cells family member 2, Membrane associated adapter molecule, Non T cell activation linker, WBSCR 5, Wbscr15, Williams Beuren syndrome chromosome region 15, Williams Beuren syndrome chromosome region 5. NCBI no.: NP_115853