PPP1R1A
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by SEC-HPLC and reducing SDS-PAGE.
ELISA, SDS, WB, MS
I1 Protein, IPP1 Protein, 0610038N18Rik Protein, I-1 Protein, pil Protein, IPP-1 Protein, protein phosphatase 1 regulatory inhibitor subunit 1A Protein, protein phosphatase 1, regulatory (inhibitor) subunit 1A Protein, protein phosphatase 1 regulatory inhibitor subunit 1A L homeolog Protein, PPP1R1A Protein, Ppp1r1a Protein, ppp1r1a.L Protein
Hintergrund
Protein phosphatase inhibitor-1(IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase(PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B). Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Protein phosphatase inhibitor, Protein phosphatase inhibitor-1 Protein phosphatase inhibitor 1, I 1, I1, Inhibitor 1, IPP 1, IPP1, PPP1R1A, Protein phosphatase 1 regulatory (inhibitor) subunit 1A, Protein phosphatase 1 regulatory subunit 1A. NCBI no.: NP_006732