VEGF121 Protein (Isoform 121)

Produktnummer ABIN667096

Produktdetails

Target: VEGF121 (Vascular Endothelial Cell Growth Factor 121 (VEGF121))

Protein-Typ: Recombinant

Proteineigenschaft: Isoform 121

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Produktmerkmale: VEGF121, 207-327aa, Human, Recombinant, E.coli

Reinheit: > 95 % by SDS PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20 mM Tris-HCl buffer (pH 8.0) containing 10 % glycerol

Lagerung: 4 °C

Antigendetails

Target: VEGF121 (Vascular Endothelial Cell Growth Factor 121 (VEGF121))

Andere Bezeichnung: VEGF 121 (VEGF121 Produkte)

Hintergrund: Vascular endothelial growth factor (VEGF) is homodimeric, heparin-binding glycoprotein involved in both angiogenesis and vasculogenesis. VEGF is expressed as multiple alternately spliced isoforms of VEGF121, 165, 189 and 206. VEGF binds to the receptor tyrosine kinases VEGF R1 (Flt-1) and VEGF R2 (KDR/Flk-1) to activate signal transduction and regulate both physiological and pathological angiogenesis. Recombinant VEGF121 protein was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: Vascular endothelial growth factor A isoform f , VPF, VEGF, VEGF-A, Vascular endothelial growth factor A isoform f MVCD1, Vascular endothelial growth factor A, Vascular permeability factor, VEGF A. NCBI no.: NP_001020541

Molekulargewicht: 14.2 kDa (122aa), confirmed by MALDI-TOF.