Nanog Protein (AA 1-305)

Produktnummer ABIN667504

Produktdetails

Target: Nanog (NANOG) (Nanog Homeobox (NANOG))

Proteineigenschaft: AA 1-305

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Produktmerkmale: NANOG, 1-305aa, Human, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 5% glycerol

Lagerung: 4 °C

Antigendetails

Target: Nanog (NANOG) (Nanog Homeobox (NANOG))

Andere Bezeichnung: NANOG (NANOG Produkte)

Synonyme: 2410002E02Rik Protein, ENK Protein, ecat4 Protein, NANOG Protein, hacp Protein, wu:fd19e04 Protein, wu:fd20a07 Protein, zgc:193933 Protein, Nanog homeobox Protein, nanog homeobox Protein, Nanog Protein, NANOG Protein, nanog Protein

Hintergrund: Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. Synonyms: Nanog homeobox, Homeobox transcription factor Nanog, homeobox transcription factor Nanog-delta 48. NCBI no.: NP_079141

Molekulargewicht: 34.6 kDa (305aa)

Pathways: Stem Cell Maintenance