AMY-1 Protein, 5730488M09Rik Protein, AW552132 Protein, AW742590 Protein, Amy-1 Protein, amy-1 Protein, AMY1 Protein, zgc:136962 Protein, MYC binding protein Protein, c-myc binding protein Protein, Myc binding protein Protein, MYCBP Protein, Mycbp Protein, mycbp Protein, TVAG_189750 Protein, PTRG_00444 Protein
Hintergrund
MYCBP, also known as c-Myc binding protein, binds to the transactivation domain of c-Myc and stimulates the activation of E-box-dependent transcription. It translocates from the cytoplasm to the nucleus during S phase when increased expression of c-Myc occurs. It has also been shown to associate with AKAP 149 and AKAP 84 in mitochondria of somatic cells and sperm, which suggests a role for MYCBP in spermatogenesis. Recombinant human MYCBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: C-Myc-binding protein, AMY-1, FLJ41056. NCBI no.: NP_036465