BIRC7
Spezies: Human
Wirt: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ELISA, SDS, WB
Livin is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING zinc finger (RZF) domain. Livin has direct interaction with several caspases including caspase-3, -7, and –9. This protein inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP. Recombinant human Livin fused to His-tag at N-terminus was expressed in E.coli and purified by conventional chromatography techniques. Synonyms: BIRC7, Baculoviral IAP repeat-containing 7, KIAP, MLIAP, RNF50, ML-IAP, KIAP, MLIAP, RNF50, Livin, Livin inhibitor of apoptosis isoform alpha, Livin inhibitor of apoptosis isoform alpha Baculoviral IAP repeat containing 7, Baculoviral IAP repeat containing protein 7, BIRC 7, Kidney inhibitor of apoptosis protein, Livin inhibitor of apotosis, RING finger protein 50, RNF 50, Melanoma inhibitor of apoptosis protein, ML IAP. NCBI no.: NP_647478