DCPS Protein (AA 1-337) (His tag)

Produktnummer ABIN7279518

Produktdetails

Target: DCPS (Decapping Enzyme, Scavenger (DCPS))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-337

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses DCPS Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: DCPS, 1-337aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT

Lagerung: 4 °C

Antigendetails

Target: DCPS (Decapping Enzyme, Scavenger (DCPS))

Andere Bezeichnung: DCPS (DCPS Produkte)

Synonyme: DCPS Protein, DCS1 Protein, HINT-5 Protein, HINT5 Protein, HSL1 Protein, 1700001E16Rik Protein, AA408441 Protein, Hint-5 Protein, decapping enzyme, scavenger Protein, DCPS Protein, dcps Protein, Dcps Protein

Hintergrund: DCPS, also known as scavenger mRNA-decapping enzyme, is belongs to the HIT family. It is necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. A scavenger decapping enzyme, DcpS was shown to hydrolyze the residual m7GpppN cap structure after the complete 3'-5' degradation of the mRNA by the exosome. DcpS releases m7GMP and is unable to cleave cap structures attached to a long RNA chain. Recombinant human DCPS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Scavenger mRNA-decapping enzyme DcpS, DCS1, HINT5. NCBI no.: NP_054745

Molekulargewicht: 40.8 kDa (357aa), confirmed by MALDI-TOF