CCL13 Protein

Produktnummer ABIN6699598

Hersteller Produkt- Nr.: 009-001-v77-0100

Produktdetails

Target: CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Hersteller Produkt- Nr.: 009-001-v77-0100

Hersteller: Rockland

Verwendungszweck: Human Monocyte Chemotactic Protein-4 (CCL13) Recombinant Protein

Aufreinigung: Monocyte Chemotactic protein-4 (CCL13) purity was determined to be greater than 95% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.

Reinheit: 95,00%

Endotoxin-Niveau: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The biological activity is determined by the ability of MCP-4 to chemoattract human monocytes and is typically between 7-75 ng/mL.

Anwendungsinformationen

Applikationshinweise:

Other: User Optimized

Application_Note: Monocyte Chemotactic Protein-4 Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Monocyte Chemotactic Protein-4 in immunological assays.

Kommentare:

Suggested_Applications: Cellular Assay

Other_Performance_Data:

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Haltbarkeit: 6 months

Antigendetails

Target: CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))

Andere Bezeichnung: CCL13 (CCL13 Produkte)

Hintergrund:

Synonyms: CK-beta-10, Monocyte chemoattractant protein 4, Monocyte chemotactic protein 4 (MCP-4), NCC-1, Small-inducible cytokine A13

Background: Monocyte Chemotactic Protein 4 (MCP-4), also called CCL13, is induced by inflammatory proteins such as IL-1 and TNFα. MCP-4 is a ligand for three different G protein coupled receptors, CCR2, CCR3 and CCR5. MCP-4 activates signaling in monocytes, T lymphocytes, eosinophils and basophils and this signaling is associated with the allergic response. Recombinant human MCP-4 is a non-glycosylated protein, containing 74 amino acids, with a molecular weight of 8.5 kDa.

UniProt: Q99616

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Phosphorylierungen bei SARS-CoV-2 Infektion