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CCL19 Protein

Rockland 010-001-c21 CCL19 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant 98,00% SDS
Rockland
Produktnummer ABIN6699625
Hersteller Produkt- Nr.: 010-001-c21
  • Target Alle CCL19 Proteine anzeigen
    CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
    Protein-Typ
    Recombinant
    Spezies
    • 10
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus
    Quelle
    • 19
    • 4
    • 1
    Escherichia coli (E. coli)
    Applikation
    SDS-PAGE (SDS)
    Hersteller Produkt- Nr.
    010-001-c21
    Hersteller
    Rockland
    Verwendungszweck
    MIP-3ß Mouse Recombinant Protein
    Aufreinigung
    Purity was determined to be greater than 98% as determined by reducing and non-reducing SDS-PAGE and analytical HPLC.
    Reinheit
    98,00%
    Endotoxin-Niveau
    Measured by LAL is < 0.01 ng/μg or < 0.1 EU/μg protein.
    Biological Activity Comment
    Recombinant mouse MIP-3-beta induces chemotaxis of human T- cells in a concentration range of 8 - 80 ng/ml.
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    Discover our top product CCL19 Protein
  • Applikationshinweise

    Other: User Optimized

    Application_Note: MIP-3ß protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-MIP-3ß in immunological assays.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 20 μL (20-200 μL)

    Konzentration
    0.1 μg/mL
    Buffer

    Buffer: 0.1 % Trifluoroacetic acid

    Stabilizer: None

    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL) . For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
    Haltbarkeit
    6 months
  • Target
    CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
    Andere Bezeichnung
    Ccl19 (CCL19 Produkte)
    Hintergrund

    Synonyms: C-C motif chemokine 19, Small-inducible cytokine A19, Epstein-Barr virus-induced molecule 1 ligand chemokine, EBI1 ligand chemokine, ELC

    Background: Macrophage Inflammatory Protein-3-beta (CCL 19, of the intercrine beta chemokine CC family) is an important secreted chemoattractant for dendritic cells, antigen-engaged B-cells, and effector-memory T-cells, signaling through the CCR7 receptor. It may play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. MIP-3ß specifically binds to chemokine receptor CCR7. MIP-3ß is strongly chemotactic for naive CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory CD4 T-cells. There is significant expression in dendritic cells in mesenteric and peripheral lymph nodes, and in spleen (T-cell zone or periarteriolar lymphatic sheath) and Peyer patches, but low expression in thymus. Recombinant mouse MIP-3-beta is a polypeptide chain consisting of 83 amino acids with a molecular weight of 9,200 Daltons.

    UniProt
    O70460
    Pathways
    Positive Regulation of Immune Effector Process
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