CXCL10 Protein

Produktnummer ABIN6699674

Hersteller Produkt- Nr.: 010-001-v69-0005

Produktdetails

Target: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Hersteller Produkt- Nr.: 010-001-v69-0005

Hersteller: Rockland

Verwendungszweck: Mouse IP-10 (CXCL10) Recombinant Protein

Aufreinigung: Ip-10 (CXCL10) purity was determined to be greater than 97% as determined by HpLC and by reducing and non-reducing SDS-pAGE.

Reinheit: 97,00%

Endotoxin-Niveau: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by its ability to chemoattract primary human T cells at 0.1-10 ng/mL.

Anwendungsinformationen

Applikationshinweise:

Other: User Optimized

Application_Note: IP-10 Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-IP-10 in immunological assays.

Kommentare:

Suggested_Applications: Cellular Assay

Other_Performance_Data:

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 5 μL (5-50 μL)

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Haltbarkeit: 6 months

Antigendetails

Target: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Andere Bezeichnung: Cxcl10 (CXCL10 Produkte)

Hintergrund:

Synonyms: 10 kDa interferon gamma-induced protein (IP-10), C7, Interferon-gamma induced protein CRG-2, small-inducible cytokine B10

Background: The chemokine IP-10 (or CXCL10) is a chemokine made by monocytes, endothelial cells and fibroblasts in response to treatment with IFNγ. IP-10 functions as a chemoattractant to cells expressing the G protein-coupled receptor, CXCR3, which is found mainly on activated T cells and NK cells. IP-10 plays an important role in Th1 type inflammatory diseases and autoimmune diseases such as, Hashimoto's thyroiditis, Graves' disease and Type 1 diabetes mellitus. Recombinant mouse IP-10 is a non-glycosylated protein, containing 77 amino acids, with a molecular weight of 8.7 kDa.

UniProt: P17515