CXCL11 Protein

Produktnummer ABIN6699679

Hersteller Produkt- Nr.: 009-001-v70-0020

Produktdetails

Target: CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Hersteller Produkt- Nr.: 009-001-v70-0020

Hersteller: Rockland

Verwendungszweck: Human ITAC (CXCL11) Recombinant Protein

Aufreinigung: ITAC (CXCL11) purity was determined to be greater than 98% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.

Reinheit: 98,00%

Endotoxin-Niveau: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The biological activity is determined by the ability to chemoattract IL-2 activated T cells at a concentration of 0.1-10 ng/mL.

Anwendungsinformationen

Applikationshinweise:

Other: User Optimized

Application_Note: ITAC Recombinant Protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-ITAC in immunological assays.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 20 μL (20-200 μL)

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Haltbarkeit: 6 months

Antigendetails

Target: CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))

Andere Bezeichnung: CXCL11 (CXCL11 Produkte)

Hintergrund:

Synonyms: B-R1, H174, Interferon gamma-inducible protein 9 (IP-9), Interferon-inducible T-cell alpha chemoattractant (I-TAC), Small-inducible cytokine B11

Background: Interferon Inducible T cell Alpha Chemokine (I-TAC), or CXCL11, expressed at high levels in leukocytes, pancreas and liver exposed to IFNα, β, and γ. I-TAC is one of three chemokines known to bind the receptor CXCR3 (the two others being CXCL9 and CXCL10 (IP-10)) to act as a chemoattractant for IL-2 activated T cells. CXCL11 differs from the other CXCR3 ligands in that it has a higher receptor affinity, thus acts as a stronger agonist. Recombinant human I-TAC is a non-glycosylated protein, containing 73 amino acids, with a molecular weight of 8.3 kDa.

UniProt: O14625