FGF22 Protein

Produktnummer ABIN6699854

Hersteller Produkt- Nr.: 009-001-u78-0005

Produktdetails

Target: FGF22 (Fibroblast Growth Factor 22 (FGF22))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Hersteller Produkt- Nr.: 009-001-u78-0005

Hersteller: Rockland

Verwendungszweck: Human Fibroblast Growth Factor-22 Recombinant Protein

Aufreinigung: Fibroblast Growth Factor-22 purity was determined to be greater than 97% as determined by analysis by HpLC, UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.

Reinheit: 97,00%

Endotoxin-Niveau: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity, as determined by the dose-dependent proliferation of 4MBr-5 cells, is typically 50-300 ng/mL.

Anwendungsinformationen

Applikationshinweise:

Other: User Optimized

Application_Note: Fibroblast Growth Factor-22 Recombinant Protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-Fibroblast Growth Factor-22 in immunological assays.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 5 μL (5-50 μL)

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Haltbarkeit: 6 months

Antigendetails

Target: FGF22 (Fibroblast Growth Factor 22 (FGF22))

Andere Bezeichnung: FGF22 (FGF22 Produkte)

Hintergrund:

Synonyms: FGFM

Background: Fibroblast Growth Factors (FGFs) are a 22 member family of proteins known to be involved in angiogenesis, wound healing and embryonic development. As a family, they bind to heparin and signal through four receptor tyrosine kinases called, FGFR1, 2, 3 and 4. Human FGF-22 is a member of the FGF-7 subfamily and is synthesized by multiple cell lines including neurons, keratinocytes and skeletal muscle myotubes. Human FGF-22 shares 86 % homology with mouse FGF-22. Recombinant human FGF-22 is a non-glycosylated protein, containing149 amino acids, with a molecular weight of 17.3 kDa.

UniProt: Q9HCT0

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung