IL-11 Protein

Produktnummer ABIN6700008

Hersteller Produkt- Nr.: 009-001-v49-0010

Produktdetails

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Hersteller Produkt- Nr.: 009-001-v49-0010

Hersteller: Rockland

Verwendungszweck: Human Interleukin-11 Recombinant Protein

Aufreinigung: Interleukin-11 purity was determined to be greater than 95% as determined by analysis by UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.

Reinheit: 95,00%

Endotoxin-Niveau: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by the dose-dependent proliferation of T11 or TF-1 cells is typically less than 2.5 ng/mL or 10 ng/mL or 4 x 10^5 units/mg or 1 x 10^5 units/mg.

Anwendungsinformationen

Applikationshinweise:

Other: User Optimized

Application_Note: Interleukin-11 Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Interleukin-11 in immunological assays.

Kommentare:

Suggested_Applications: Cellular Assay

Other_Performance_Data:

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 10 μL (10-100 μL)

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Haltbarkeit: 6 months

Antigendetails

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Andere Bezeichnung: IL11 (IL11 Produkte)

Hintergrund:

Synonyms: AGIF (Adipogenesis Inhibitory Factor), Oprelvekin

Background: Interleukin 11 (IL-11) is a pleotropic cytokine closely related to IL-6 in function, but is overall one of the lesser characterized interleukins. In hematopoietic cell populations, IL-11 is thought to induce megakaryocyte differentiation. In non-hematopoietic populations, IL-11 is thought to be able to stimulate hepatic acute-phase proteins. Human IL-11 can stimulate murine cells. Recombinant human IL-11 is a non-glycosylated protein, containing 179 amino acids, with a molecular weight of 19.3 kDa.

UniProt: P20809

Pathways: JAK-STAT Signalweg, Negative Regulation of Hormone Secretion