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IL12 Protein

Rockland 010-001-v51-0010 IL12 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant 95,00% SDS
Rockland
Produktnummer ABIN6700020
Hersteller Produkt- Nr.: 010-001-v51-0010
  • Target Alle IL12 Proteine anzeigen
    IL12 (Interleukin 12 (IL12))
    Protein-Typ
    Recombinant
    Spezies
    • 20
    • 10
    • 4
    • 1
    Maus
    Quelle
    • 14
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Applikation
    SDS-PAGE (SDS)
    Hersteller Produkt- Nr.
    010-001-v51-0010
    Hersteller
    Rockland
    Verwendungszweck
    Mouse Interleukin-12 Recombinant Protein
    Aufreinigung
    Interleukin-12 purity was determined to be greater than 95% as determined by reducing and non-reducing SDS-pAGE.
    Reinheit
    95,00%
    Endotoxin-Niveau
    Measured by LAL is typically ≤ 1 EU/μg protein.
    Biological Activity Comment
    The activity is determined by the induced expression of CD25 on CD8+ mouse T cells and is typically detectable starting at 0.1 ng/mL.
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    Discover our top product IL12 Protein
  • Applikationshinweise

    Other: User Optimized

    Application_Note: Interleukin-12 Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Interleukin-12 in immunological assays.

    Kommentare

    Suggested_Applications: Cellular Assay

    Other_Performance_Data:

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 10 μL (10-100 μL)

    Buffer
    Lyophilized in 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5.
    Konservierungsmittel
    Without preservative
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
    Haltbarkeit
    6 months
  • Target
    IL12 (Interleukin 12 (IL12))
    Andere Bezeichnung
    Il12a/Il12b (IL12 Produkte)
    Hintergrund

    Synonyms: NKSF, CLMF

    Background: Interleukin-12 (IL-12) is an important mediator of cellular-immunity produced by dendritic cells, macrophages and B cells when stimulated with antigen. IL-12 is involved in differentiating precursor helper T cells to Th1 and/or Th2 subtypes and promotes the production of IFN gamma and TNF alpha. Mouse IL-12 is active on human and mouse cells. Recombinant mouse IL-12 is a glycosylated, disulfide-linked heterodimer. It is containing one p35 su

    UniProt
    P43432
    Pathways
    JAK-STAT Signalweg, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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