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IL-21 Protein

Rockland 009-001-v61-0100 IL21 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 95,00% SDS
Rockland
Produktnummer ABIN6700077
Hersteller Produkt- Nr.: 009-001-v61-0100
  • Target Alle IL-21 (IL21) Proteine anzeigen
    IL-21 (IL21) (Interleukin 21 (IL21))
    Protein-Typ
    Recombinant
    Spezies
    • 31
    • 12
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 28
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    SDS-PAGE (SDS)
    Hersteller Produkt- Nr.
    009-001-v61-0100
    Hersteller
    Rockland
    Verwendungszweck
    Human Interleukin-21 Recombinant Protein
    Aufreinigung
    Interleukin-21 purity was determined to be greater than 95% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
    Reinheit
    95,00%
    Endotoxin-Niveau
    Measured by LAL is typically ≤ 1 EU/μg protein.
    Biological Activity Comment
    The activity is determined by the dose-dependent stimulation of B9 cells and is typically less than 50 ng/mL.
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  • Applikationshinweise

    Other: User Optimized

    Application_Note: Interleukin-21 Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Interleukin-21 in immunological assays.

    Kommentare

    Suggested_Applications: Cellular Assay

    Other_Performance_Data:

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 100 μL

    Buffer

    Buffer: 0.01 M Sodium Phosphate, pH 7.5

    Stabilizer: None

    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
    Haltbarkeit
    6 months
  • Target
    IL-21 (IL21) (Interleukin 21 (IL21))
    Andere Bezeichnung
    IL21 (IL21 Produkte)
    Hintergrund

    Synonyms: Za11

    Background: Interleukin-21 (IL-21) is a member of the common gamma-chain family of cytokines (includes IL-2, IL-4, IL-7, IL-9, IL-13, and IL-15) and is expressed by activated CD4+ T cells. IL-21 has a private receptor known as IL-21R, which is expressed on T, B, and NK cells. Within the B cell lineage, IL-21 regulates IgG1 production and cooperates with IL-4 for the production of multiple Ab classes in vivo. Initial studies have demonstrated that IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, natural killer, and dendritic cells. Recombinant human IL-21 is a non-glycosylated protein, containing 133 amino acids, with a total molecular weight of 15.5 kDa.

    UniProt
    Q9HBE4
    Pathways
    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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