IL-21 Protein
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- Target Alle IL-21 (IL21) Proteine anzeigen
- IL-21 (IL21) (Interleukin 21 (IL21))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Applikation
- SDS-PAGE (SDS)
- Hersteller Produkt- Nr.
- 009-001-v61-0100
- Hersteller
- Rockland
- Verwendungszweck
- Human Interleukin-21 Recombinant Protein
- Aufreinigung
- Interleukin-21 purity was determined to be greater than 95% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
- Reinheit
- 95,00%
- Endotoxin-Niveau
- Measured by LAL is typically ≤ 1 EU/μg protein.
- Biological Activity Comment
- The activity is determined by the dose-dependent stimulation of B9 cells and is typically less than 50 ng/mL.
- Top Product
- Discover our top product IL21 Protein
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- Applikationshinweise
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Other: User Optimized
Application_Note: Interleukin-21 Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Interleukin-21 in immunological assays.
- Kommentare
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Suggested_Applications: Cellular Assay
Other_Performance_Data:
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
- Buffer
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Buffer: 0.01 M Sodium Phosphate, pH 7.5
Stabilizer: None
- Konservierungsmittel
- Without preservative
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
- Haltbarkeit
- 6 months
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- Target
- IL-21 (IL21) (Interleukin 21 (IL21))
- Andere Bezeichnung
- IL21 (IL21 Produkte)
- Hintergrund
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Synonyms: Za11
Background: Interleukin-21 (IL-21) is a member of the common gamma-chain family of cytokines (includes IL-2, IL-4, IL-7, IL-9, IL-13, and IL-15) and is expressed by activated CD4+ T cells. IL-21 has a private receptor known as IL-21R, which is expressed on T, B, and NK cells. Within the B cell lineage, IL-21 regulates IgG1 production and cooperates with IL-4 for the production of multiple Ab classes in vivo. Initial studies have demonstrated that IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, natural killer, and dendritic cells. Recombinant human IL-21 is a non-glycosylated protein, containing 133 amino acids, with a total molecular weight of 15.5 kDa.
- UniProt
- Q9HBE4
- Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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