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GDNF Protein

Rockland 010-001-v10-0010 GDNF Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant 98,00%
Rockland
Produktnummer ABIN6700939
Hersteller Produkt- Nr.: 010-001-v10-0010
  • Target Alle GDNF Proteine anzeigen
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    Protein-Typ
    Recombinant
    Spezies
    • 11
    • 5
    • 3
    • 1
    Maus
    Quelle
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Hersteller Produkt- Nr.
    010-001-v10-0010
    Hersteller
    Rockland
    Verwendungszweck
    Mouse Glial Derived Neurotrophic Factor Recombinant Protein
    Aufreinigung
    Glial Derived Neurotrophic Factor purity was determined to be greater than 98% as determined by analysis by reducing and non-reducing SDS-pAGE.
    Reinheit
    98,00%
    Endotoxin-Niveau
    Measured by LAL is typically ≤ 1 EU/μg protein.
    Biological Activity Comment
    The activity is determined by the dose-dependent proliferation of C6 cells and is typically less than 1 μg/mL.
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  • Applikationshinweise

    Other: User Optimized

    Application_Note: Glial Derived Neurotrophic Factor Recombinant Protein has been tested by biological activity and is suitable as a control for polyclonal or monoclonal anti-Glial Derived Neurotrophic Factor in immunological assays.

    Kommentare

    Suggested_Applications: Cellular Assay

    Other_Performance_Data:

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 10 μL (10-100 μL)

    Buffer

    Buffer: 0.1 % Trifluoroacetic acid

    Stabilizer: None

    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
    Haltbarkeit
    6 months
  • Target
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    Andere Bezeichnung
    Gdnf (GDNF Produkte)
    Hintergrund

    Synonyms: ATF-1

    Background: Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a neurotrophic factor that is closely related to other neurotrophic factors, such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes RET and GFRα1-4, to promote dopamine uptake, survival and differentiation of neurons. Recombinant mouse GDNF is a non-glycosylated homodimer, containing two 135 amino acid chains, with a total molecular weight of 30.2 kDa.

    UniProt
    P48540
    Pathways
    RTK Signalweg, Synaptic Membrane, Tube Formation, Autophagie, Smooth Muscle Cell Migration
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