GDNF Protein
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- Target Alle GDNF Proteine anzeigen
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
- Protein-Typ
- Recombinant
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Spezies
- Ratte
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Quelle
- Escherichia coli (E. coli)
- Hersteller Produkt- Nr.
- 012-001-v10-0010
- Hersteller
- Rockland
- Verwendungszweck
- Rat Glial Derived Neurotrophic Factor Recombinant Protein
- Aufreinigung
- Glial Derived Neurotrophic Factor purity was determined to be greater than 98% as determined by analysis by reducing and non-reducing SDS-pAGE.
- Reinheit
- 98,00%
- Endotoxin-Niveau
- Measured by LAL is typically ≤ 1 EU/μg protein.
- Biological Activity Comment
- The activity is determined by the dose-dependent proliferation of C6 cells and is typically less than 0.1 μg/mL.
- Top Product
- Discover our top product GDNF Protein
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- Applikationshinweise
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Other: User Optimized
Application_Note: Glial Derived Neurotrophic Factor Recombinant Protein has been tested by biological activity and is suitable as a control for polyclonal or monoclonal anti-Glial Derived Neurotrophic Factor in immunological assays.
- Kommentare
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Suggested_Applications: Cellular Assay
Other_Performance_Data:
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 10 μL (10-100 μL)
- Buffer
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Buffer: 0.01 M Sodium Phosphate, pH 7.5
Stabilizer: None
- Konservierungsmittel
- Without preservative
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
- Haltbarkeit
- 6 months
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- Target
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
- Andere Bezeichnung
- Gdnf (GDNF Produkte)
- Hintergrund
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Synonyms: ATF-1
Background: Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a neurotrophic factor that is closely related to other neurotrophic factors, such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes RET and GFRα1-4, to promote dopamine uptake, survival and differentiation of neurons. Recombinant rat GDNF is a non-glycosylated homodimer, containing two 135 amino acid chains, with a total molecular weight of 30.1 kDa.
- UniProt
- Q07731
- Pathways
- RTK Signalweg, Synaptic Membrane, Tube Formation, Autophagie, Smooth Muscle Cell Migration
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